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Table 5. Tissue specific transcripts

Tissue specific transcripts from colon epithelium, brain, melanocytes, keratinocytes, breast epithelium, lung epithelium, prostate, and kidney epithelium.  The number in parentheses adjacent to the tissue type indicates the percent of transcripts exclusively expressed in a given tissue at > 10 copies per cell.  Transcript tag denotes the 10bp tag adjacent to 4bp NlaIII anchoring enzyme site, Copies/cell denotes the transcript copies per cell expressed, and UniGene Description provides a description of each matching UniGene cluster (from UniGene Build No. 67).

Colon epithelium (1.76%)

Tag sequence

Copies/cell

Unigene Description

ATACTCCACT

431

Guanylate cyclase activator 2 (guanylin, intestinal, heat-stable)

TCAGCTGCAA

220

No match

GTCATCACCA

174

H.sapiens mRNA for GCAP-II/uroguanylin precursor

CCTTCAAATC

141

Carbonic anhydrase I

ACACCCATCA

89

No match

CCAACACCAG

86

No match

AATAGTTTCC

70

Pregnancy-specific beta-1 glycoprotein 6

CCAGGCGTCA

55

No match

GAACAGCTCA

55

ESTs

TACTCGGCCA

46

No match

GGGGGAGAAG

37

ESTs

AGTGGGCTCA

34

No match

GAGCACCGTG

34

No match

GATCTATCCA

31

ESTs

GAACGCCAGA

28

No match

GCCCTCGGAG

28

ESTs

ACAAGCCTAG

28

No match

GTCACAGGAA

28

No match

GCCCTCGGAG

28

Human homeobox protein Cdx2 mRNA, complete cds

CTAGGATGAT

28

ESTs

CCAACTATCG

24

No match

CTGACGGGGA

24

ESTs

GAGGGTTTTA

24

Homo sapiens C19steroid specific UDP-glucuronosyltransferase mRNA, complete cds

GGGGTCCCAT

24

No match

GCCAGGTCAC

21

No match

AGAACACCAA

21

No match

AATCCCGCCC

21

Homo sapiens hAQP8 mRNA for aquaporin 8, complete cds

ACACTGCCTC

18

No match

AGAGTCCAGG

18

Homo sapiens carcinoembryonic antigen (CGM2) mRNA, complete cds

CCAGACGTAG

18

No match

GAGGCCCCCG

18

No match

CTGTGTGCCC

15

ESTs, Weakly similar to tryptase-III [H.sapiens]

GAGAGGATGG

15

ESTs

GGCTGAACCA

15

No match

CCAAATCATT

15

No match

ACGGCTGGGC

15

No match

ACCTTCATCT

15

EST

AGGGCTTGAG

15

No match

ACCTTCATCT

15

Human rearranged metabotropic glutamate receptor type II (GLUR2) mRNA, complete cds

TCAGGCCAGA

15

No match

CTGTGTGCCC

15

ESTs

GGATGTCAAC

15

Human RecA-like protein (hREC2) mRNA, complete cds

ATCTGGAGCA

15

Alcohol dehydrogenase 1 (class I), alpha polypeptide

GAGAGGATGG

15

INTEGRAL MEMBRANE PROTEIN E16

ATCTGGAGCA

15

Alcohol dehydrogenase 3 (class I), gamma polypeptide

GGATGTCAAC

15

Polymeric immunoglobulin receptor

CACAGACACA

12

No match

TGCTCCTAAC

12

No match

TATACCCGGA

12

No match

TATCCTGATG

12

No match

GGCCCTCCCG

12

No match

GTAGCGATGG

12

Pim-1 oncogene

GCAGGTTGTG

12

No match

TGGGAACCGG

9

No match

ACACCTCTCT

9

No match

GGAAAACAGG

9

No match

CAGGCGGCAC

9

No match

CAGGTTGGTC

9

Homo sapiens hRVP1 mRNA for RVP1, complete cds

GGGATATAAA

9

No match

GTGGAAAATC

9

No match

GTGTGTGAAT

9

No match

ATGTGACACT

9

No match

ATGGTGTAAT

9

ESTs

TCACATTGAT

9

H.sapiens mRNA for LI-cadherin

TAACTAAACA

9

No match

TGCCCGGGTC

9

No match

TAGTCGGAAA

9

No match

GCTATACGGG

9

No match

TCACACCCCA

9

No match

CTGCCCGAAC

9

ESTs

AGTCACCTCT

9

No match

TCATTGGTTT

9

No match

TCCTCTCCTC

9

No match

CCTCTCGGCC

9

No match

CCACTGAAGT

9

No match

CTGGCTTGCT

9

No match

GAAAACAGAA

9

EST

AAAGCACGTC

9

No match

GAAAACAGAA

9

ESTs, Weakly similar to synapse-associated protein sap47-1 [D.melanogaster]

TTGATTCCAT

9

No match

AAACAGGCAC

9

No match

CTTACAGTCC

9

No match

GAATGGACTC

9

No match

GAACCCAAAC

9

No match

GAAAACAGAA

9

ESTs

Brain (1.36%)

ACTTTGTCCC

237

Glial fibrillary acidic protein

GTGCGAATCC

117

ESTs

CAAAAAGTTA

53

ESTs

TTAACTTTAT

49

Homo sapiens neuroendocrine-specific protein A (NSP) mRNA, complete cds

CAGCCAAATG

43

ESTs

GCCTGTGGTG

41

Homo sapiens LY6H mRNA, complete cds

CTTAGGGACA

39

ESTs

TTGGAGGTGA

33

ESTs

ATTCCATTTC

30

ESTs

ATTCCATTTC

30

ESTs, Highly similar to RAS-RELATED PROTEIN RAB-10 [Canis familiaris]

AGAGAGCGGA

28

Human guanine nucleotide-binding regulatory protein (Go-alpha) gene

TTCTCAATAC

28

Homo sapiens mRNA for synaptopodin

CATCCTCCCA

28

No match

GTATCGATTT

24

Homo sapiens GABA-B receptor mRNA, complete cds

TTGTAAACAG

22

ESTs, Weakly similar to cyclin I [H.sapiens]

GCCCTGTATT

22

ESTs

CCACATTGCC

22

Homo sapiens chromosome 7q22 sequence

CAGGGCAACG

22

No match

AAAAGCAAAT

22

Human mRNA for MOBP (myelin-associated oligodendrocytic basic protein), complete cds, clone hOPRP1

ACCAATCCTA

21

Human guanine nucleotide-binding regulatory protein (Go-alpha) gene

CTGTGTGTCC

19

AXONIN-1 PRECURSOR

TCAGACAATA

18

ESTs

TGGTGAGATG

18

ESTs

ATTTTTTGTT

18

ESTs

ACATTGAGTC

18

Homo sapiens mRNA for MEGF4, partial cds

GTCAGTCTAC

16

Glutamate receptor, metabotropic 3

GTCCCACTTC

16

ESTs

GGGGCCCGAA

16

No match

TGACTCACCC

15

Homo sapiens calmodulin-stimulated phosphodiesterase PDE1B1 mRNA, complete cds

GACAGCGACA

15

No match

GGTGTACATA

15

ESTs

TAGCTATAAA

15

ESTs

GGTGTACATA

15

ESTs

GTTTCATTTT

15

ESTs

AATAAATTGC

15

ESTs

GTTTCATTTT

15

ESTs

ACACATTGTA

15

No match

TACCTATTGT

15

ESTs

TTTAGCAGAA

15

Homo sapiens cyclin E2 mRNA, complete cds

TTTAGCAGAA

15

ESTs

CAATTTATGA

13

ESTs

GTGAAGGTTT

13

Homo sapiens (huc) mRNA, complete cds

TGGACTTTTA

13

ESTs

CGATGCCACG

13

No match

GTGAAGGTTT

13

Neuron-specific RNA recognition motifs (RRMs)-containing protein [human, hippocampus, mRNA, 1992 nt]

TGGACTTTTA

13

ESTs

CCTTCTTGTC

13

No match

TCCATTCAAG

13

Human clone 23586 mRNA sequence

CCTATGTATC

12

No match

ACGGACCAAT

12

No match

TATTATCTTG

12

ESTs

ACTTTATACG

12

ESTs

ACTTTATACG

12

ESTs, Weakly similar to EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8 [H.sapiens]

CGCAGTCCCC

12

BETA-NEOENDORPHIN-DYNORPHIN PRECURSOR

TGTAGTGCTC

12

No match

CTGCTTAAGT

12

ESTs, Weakly similar to unknown [H.sapiens]

ACAAGTGGAA

12

Human mRNA for KIAA0027 gene, partial cds

AATCCCAATG

10

Homo sapiens mRNA for KIAA0283 gene, partial cds

ACTATGCATC

10

No match

ACGAGTCATT

10

ESTs

TTACATTGTA

10

Homo sapiens clone 24461 mRNA sequence

ATGCCCCCTC

10

ESTs, Highly similar to HYPOTHETICAL 52.2 KD PROTEIN ZK512.6 IN CHROMOSOME III [Caenorhabditis elegans]

TTTTATTCAT

10

ESTs

ACAGAGCATT

10

No match

TGACCAATAG

10

No match

AATCCCAATG

10

Plastin 1 (I isoform)

Keratinocytes (0.09%)

GCGAACTGGG

18

ORPHAN RECEPTOR TR4

GCAACACTAA

11

No match

GTAATGGATT

11

No match

AGCAGACGTG

11

No match

Breast epithelium (0.14%)

GGATTCGGTC

17

No match

CGGAAGGCGG

14

No match

TGTAAGTACG

14

No match

GATCAGTCAT

11

No match

GCTCAGAGTT

11

No match

Lung epithelium (0.17%)

TAACCTCCCC

241

No match

AGGAACAACT

16

No match

GGGTCCGTGG

16

No match

TAGCAAAATA

13

No match

GCTGTGCACA

11

No match

CAGAAAATCA

11

No match

GATTTGCTGG

11

No match

Melanocytes (0.93%) 

GTGCCATTCT

309

No match

GATATTTGTC

108

5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE PRECURSOR

TATGATTTTA

106

ESTs

TCACTGCAAC

73

5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE PRECURSOR

CCCAGTCACA

57

ESTs, Weakly similar to LACTOSE PERMEASE [Escherichia coli]

TATGAGAACC

46

ESTs, Highly similar to HIGH AFFIMMUNOGLOBULIN GAMMA FC RECEPTOR I PRECURSOR [Homo sapiens]

GAGTTTAGTG

43

No match

CTCCACTCTG

41

No match

ATCCAGTGAC

38

No match

TGATCTTGAG

38

ESTs, Moderately similar to PAS protein 5 [H.sapiens]

AATGGCTGTT

33

Human melanoma antigen recognized by T-cells (MART-1) mRNA

ATACTAAAAA

33

Human cysteine protease CPP32 isoform alpha mRNA, complete cds

ATACTAAAAA

33

EST

GTTTATTAAA

27

PROTEIN-TYROSINE PHOSPHATASE ZETA PRECURSOR

AGAAATCAGT

24

No match

TTGGATATTA

24

Homo sapiens clone 23785 mRNA sequence

AATTGAGTAG

24

Human DNA sequence from PAC 257A7 on chromosome 6p24. Contains two unknown genes and ESTs, STSs and a GSS

TGAGTGCTGC

24

No match

GCAGTACAGT

22

No match

GAATTCAGGA

19

Homo sapiens mRNA for KIAA0679 protein, partial cds

GACTTCTTTA

19

No match

GAATTCAGGA

19

Homo sapiens melastatin 1 (MLSN1) mRNA, complete cds

GTTTATACTG

19

No match

GAATTCAGGA

19

Homo sapiens mRNA for synaptosome associated protein of 23 kilodaltons, isoform A

GCCCGTGTAG

16

Msh (Drosophila) homeo box homolog 1 (formerly homeo box 7)

TGGGGTGTGC

16

Homo sapiens thyroid receptor interactor (TRIP8) mRNA, 3' end of cds

AATTTTTATG

14

Interferon regulatory factor 4

TCAGTGTCTG

14

ESTs

GGAGGTCAGC

14

ESTs

TTCTTCTCAA

14

ESTs

TTCTTCTCAA

14

ESTs

GGTTGTCTCT

14

ESTs, Weakly similar to line-1 protein ORF2 [H.sapiens]

CTTTGTTTAC

14

No match

CACTATAGAA

14

No match

TTTGGTTACA

11

EST

TCAAAACAAT

11

Human R kappa B mRNA, complete cds

TTTGGTTACA

11

Homo sapiens clone 23688 mRNA sequence

TATAGAGCAA

11

No match

TAATAACCAG

11

No match

TTCTATACTG

11

No match

GGAATACGGC

11

No match

Prostate (0.05%)

GAACTGGCA

9

No match

AATGTTGGGG

9

No match

Kidney Epithelium (0.27%)

CGACAAACTA

12

No match

GTAGCACAGA

12

No match

ACCGTCAATC

12

No match

TGGATCAGTC

12

Human mRNA for KIAA0259 gene, partial cds

TGGCTCGGTC

12

EST

GCGACTGCGA

12

No match

GCACTAGCTG

9

No match

GCGGCCGGTT

9

No match

CGGCAGTCCC

9

No match

GCCCACCTGT

9

No match

CGGCGGATGG

9

No match

CCCCAGGCCG

9

No match

CCCATTCCAA

9

No match

TCAAGAGGTG

9

No match

ATAACTGTTG

9

Human HFREP-1 mRNA for unknown protein, complete cds

 

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