Table 4. Detection of transcripts in various tumor types by RT-PCR and in situ hybridization (ISH).

The "+" sign indicates the presence of a robust RT-PCR product or stong positive staining of vessels by in situ hybridization. The "-" sign indicates an undetectable signal by in situ hybridization or an absent or barely detectable transcript by RT-PCR. The "+/-" sign indicates a very weak signal in a limited number vessels by in situ hybridization. "ND" indcates not determined.

TEM1
TEM3
TEM4
TEM5
TEM7
TEM8
TEM9
vWF
Hevin
RT-PCR
ColonNor.
-
-
-
-
-
-
-
+
ND
Colon Tum.
+
+
+
+
+
+
+
+
ND
ISH
ColonNor.
-
-
-
-
-
-
-
+
+
Colon Tum.
+
+
+
+
+
+
+
+
+
Liver Met.
+
+/-
+
+
+
+
+
+/-
ND
Lung Tum.
+
ND
+
+
+
+
+
+
+
Brain Tum.
+
ND
ND
ND
+
ND
ND
+
+*
Corpus Lut.
+
+
+
+
+
-
+
+
+
Wound
+
ND
+
ND
+/-
+/-
ND
+
+

* hevin was localized to both endothelial cells and malignant cells in brain tissue.

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