Table 3. Previously characterized and novel Normal Endothelial Markers (NEMs).

    The top 33 tags with the highest normal EC (N-EC's) to tumor EC (T-EC's) tag ratios are listed in descending order. To calculate tag ratios, a value of 0.5 was assigned in cases where zero tags were observed. The SAGE libraries are the same as those listed in Table 1. Tag numbers for each group were normalized to 100,000 transcripts. A 'Description' of the gene product corresponding to each tag is given, followed by alternative names in parenthesis.
no. Tag Sequence N-EC's T-EC's HUVEC HMVEC Cell Lines Description
1 TCTCACGTCTC 26 0 0 0 0 mucosal vascular addressin cell adhesion molecule 1
2 CTAGCGTTTTA 19 0 4 14 0 serum deprivation response (phosphatidylserine-binding protein)
3 GTGGCTGACGC 18 0 1 0 0 ESTs / intercellular adhesion molecule 4
4 CTCTTAAAAAA 34 1 1 0 0 small inducible cytokine subfamily A (Cys-Cys), member 14
5 TGGGAAGAGGG 16 0 3 4 1 ESTs
6 GTTTAAGGATG 16 0 0 0 0 ESTs
7 CTTTGTTTTGC 15 0 56 32 1 endothelin 1
8 ATTGCCAATCT 14 0 0 4 0 TU3A protein
9 TGTTGAAAAAA 21 1 1 0 0 E-selectin (endothelial adhesion molecule 1)
10 ACAAAAAGGCC 21 1 0 6 0 TU3A protein
11 AAGATGCACAC 21 1 1 1 1 phosphodiesterase I - nucleotide pyrophosphatase 2 (autotaxin)
12 GTAGAGGAAAA 10 0 0 9 0  
13 TTGTTCAAGGG 10 0 0 1 0 ESTs
14 CTCTTCAAAAA 19 1 1 0 0 small inducible cytokine subfamily A, member 14
15 TATTAAAATAG 18 1 6 9 1 transforming growth factor, beta receptor II (70-80kD)
16 GAATTCACCAG 9 0 1 14 0 ESTs
17 AAGGAGAACTG 9 0 0 0 0 small inducible cytokine subfamily A, member 14
18 AATATCTGACT 9 0 2 2 2 active BCR-related gene
19 TCAGTGACCAG 17 1 4 7 2 protein kinase C eta
20 GCAAAGTGCCC 32 2 1 5 0 ESTs
21 TAAATACTTGT 8 0 2 0 0 ESTs
22 GTCACTAATTT 8 0 1 0 0 ESTs
23 ATAACCTGCAG 8 0 0 0 0 signaling lymphocytic activation molecule
24 TGCATCTGTGC 46 3 1 1 0 ESTs / glycogenin 2
25 TAAAGGCACAG 15 1 4 3 0 LIM binding domain 2
26 GACCGCGGCTT 73 5 11 7 0 claudin 5
27 ACTCCGGTGTG 14 1 0 8 0 ESTs
28 CTTCTCACCTA 27 2 3 1 0 GTP-binding protein
29 TCGTGCTTTGT 13 1 0 0 0 ESTs
30 GAGCAGTGCTG 13 1 4 2 1 feline sarcoma viral (v-fes) - Fujinami avian sarcoma viral (v-fps) homolog
31 CTCTAAAAAAA 10 1 0 1 0 ESTs
32 GAAACCCGGTA 10 1 0 0 1 phospholipase C, beta 4
33 AACACAGTGCC 10 1 7 15 1 ESTs

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